Methyl N-propyl Ether: a Report of a Clinical Trial
نویسنده
چکیده
METHYL N-PIqOPYL ETHER was first described by Chancel in 1869, but its valuable anaesthetm properties were not apprecmted unlal its inclusion in the long senes of ethers tested by Krantz and has co-workers m the United States. The clinical trials of methyl n-propyl ether fol/owing Krantz's original description of its anaesthetic properties and pharmacology m 1946 (1) showed that it might be supermr to diethyl ether as an inhalahon anaesthelac, in having the useful properties of diethyl ether in enhanced degree without some o~ its undesirable features. Many further reports have stressed the advantages of methyl n-propyl ether over dmthyl ether, and yet the agent has not gamed any wade acceptance m clinical anaesthesia. It was m an attempt to determine the reasons for thas lack of acceptance of this agent that the following study of methyl n-propyl ether was carried out.
منابع مشابه
Methyl-n-propyl ether.
ME T H Y L N P R O P Y L ETHER is an isomer of di-ethyl ether and possesses the formula CHs-O(CHI)J-CHJ. The physical properties of the two drugs are similar, and the vapour pressure curve of methyl-n-propyl ether is such that it may be used in the Oxford Vaporizer No. 1 without any alteration in the calibration of the instrument (see Figure). Methyl-n-propyl ether has a very unpleasant pungent...
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